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Matt’s Contact Information

859.394.0017 Tel
859.394.0017 Fx
304.730.7011 Cell

Matt’s Secretary

Vaughn Summers


Matt Mains grew up around the legal world with a father who served as a Kentucky circuit judge for over 20 years but took a few detours before becoming an attorney. He credits those detours and his background in biochemical science in providing him unique insight into his work.

Matt is an experienced litigator who has spent nearly ten years defending medical providers, facilities and hospital systems. His strong background in science aids him in understanding many of the disease processes involved in the underlying issues in a medical malpractice case on an anatomical, physiological and biochemical level.

When asked about his true passion at work, Matt focuses on bringing clients relief with his counsel. “I am passionate about ensuring that medical providers and health care professionals are treated fairly by the legal system. Knowing that they can focus their attention on patient care and not on practicing defensive medicine provides them peace of mind.”

Outside of the courtroom, Matt spends most of this time with family. When he is not coaching and attending the various extracurricular activities of his four children, you can find Matt cheering on the Kentucky Wildcats and the Cincinnati Reds.


  • J.D., University of Kentucky, College of Law (2011)
  • M.S. in Biomedical Science, Medical University of South Carolina (2007)
  • B.S., magna cum laude, Agricultural Biotechnology, University of Kentucky (2003)

Court Admissions

  • Kentucky Supreme Court
  • Kentucky Court of Appeals
  • United States District Court for the Eastern District of Kentucky
  • West Virginia Supreme Court of Appeals
  • United States District Court for the Southern District of West Virginia

Professional Involvement

  • Kentucky Bar Association
  • West Virginia Bar Association
  • American Bar Association
  • Defense Research Institute (DRI)
  • Defense Trial Counsel of West Virginia

Awards & Honors

  • WV Super Lawyers, Rising Star – Medical Malpractice -Defense (2019 – 2021)
  • CALI award for excellence: Intellectual Property and Copyright Law
  • American Heart Association Predoctoral Fellowship Award (2006 – 2007)
  • National Institutes of Health Predoctoral Fellowship Award (2005 – 2006)
  • Merit Scholar Recipient (2000 – 2003)

Written Work

  • Ford RL, Mains IM, Hilton EJ, Reeves ST, Stroud RE, Crawford FA Jr, Ikonomidis JS, Spinale FG. Endothelin-A receptor inhibition after cardiopulmonary bypass: cytokines and receptor activation. Annals of Thoracic Surgery. 2008 Nov;86(5):1576-83.
  • McEvoy MD, Taylor AG, Zavadzkas JA, Mains IM, Ford RL, Stroud RE, Jeffords LB, Beck CU, Reeves ST, Spinale FG. Aprotinin exerts differential and dose-dependent effects on myocardial contractility, oxidative stress, and cytokine release after ischemia-reperfusion. Annals of Thoracic Surgery. 2008 Aug;86(2):568-75.
  • Spruill LS, Lowry AS, Stroud RE, Squires CE, Mains IM, Flack EC, Beck C, Ikonomidis JS, Crumbley AJ, McDermott PJ, Spinale FG. Membrane type-1 matrix metalloproteinase transcription and translation in myocardial fibroblasts from patients with normal left ventricular function and from patients with cardiomyopathy. Am Journal of Physiology: Cell Physiology. 2007 Oct;293(4): C1362-73.
  • Lindsey ML, PG Escobar, Mukherjee R, Goshorn DK, Sheats NJ, Bruce JA, Mains IM, Hendrick JK, Hewett KW, Gourdie RG, Matrisian LM, Spinale FG. Matrix Metalloproteinase-7 Affects Connexin-43 Levels, Electrical Conduction, and Survival Following Myocardial Infarction. Circulation. 2006 Jun 27;113(25):2919-28.
  • Sporici RA, Hodskins JS, Locasto DM, Meszaros LB, Ferry AL, Weidner AM, Rinehart CA, Bailey JC, Mains IM, Diamond SE. Repression of the prolactin promoter: a functional consequence of the heterodimerization between Pit-1 and Pit-1 beta. Journal of Molecular Endocrinology. 2005Oct;35(2):317-31.
  • Squires CE, Escobar GP, Payne JF, Leonardi RA, Goshorn DK, Sheats NJ, Mains IM, Mingoia JT, Flack EC, Lindsey ML. Altered fibroblast function following myocardial infarction. Journal of Molecular Cell Cardiology. 2005Oct;39(4):699-707.